Primary cervical neuroblastoma in children: clinical case and review of the literature

Authors

  • Dr Mouangue-Mbonjo Louise Lecturer / ENT and Maxillofacial Surgery Department
  • David Mindja Eko Department of ophtalmology and Otorhinolaryngology
  • Astadjam Dairou Department of Surgery and Specialties, Faculty of Medecine and Pharmaceutical Science
  • François Djomou Department of ophtalmology and Otorhinolaryngology

DOI:

https://doi.org/10.5281/zenodo.14580572

Keywords:

cervical, neuroblastoma, child, surgery, computed tomography

Abstract

Cervical neuroblastomas are rare tumors in children and are associated with poor outcomes. Their diagnosis requires clinical and paraclinical examinations. Imaging is key in determining the operability and search for metastases. Treatment depends on disease stage. Of note, there is limited existing data on this entity. We report a case of a 4-year-old female with cervical neuroblastoma stage 2B as per the International Neuroblastoma Staging System (INSS). She underwent surgery and adjuvant chemotherapy with favorable outcomes. Cervical neuroblastomas should be suspected in patients with a neck mass and constitutional symptoms. Treatment depends on the tumor stage.

Author Biographies

Dr Mouangue-Mbonjo Louise, Lecturer / ENT and Maxillofacial Surgery Department

Lecturer / ENT and Maxillofacial Surgery Department, Yaounde Central Hospital, Department of Otorhinolaryngology and Cervico-maxillofacial Surgery, Yaounde Central Hospital, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon

David Mindja Eko, Department of ophtalmology and Otorhinolaryngology

Department of ophtalmology and Otorhinolaryngology University of Yaounde I, Cameroon., Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

Astadjam Dairou, Department of Surgery and Specialties, Faculty of Medecine and Pharmaceutical Science

Department of Surgery and Specialties, Faculty of Medecine and Pharmaceutical Science, University of Douala, Cameroon

François Djomou, Department of ophtalmology and Otorhinolaryngology

Department of ophtalmology and Otorhinolaryngology University of Yaounde I, Cameroon., Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

References

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Cohn SL, Pearson ADJ, London WB, Monclair T, Ambros PF, Brodeur GM, et al. The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report.J ClinOncol2009;27:289–97. https://doi.org/10.1200/JCO.2008.16.6785.

G. Dauphin , P. Costa de Araujo, P. Forget, P. Leroy, L. Rausin, M. Demarche. Présentation clinique atypique d’un neuroblastome chez un nourrisson Rev Med Liège 2013; 68 : 2 : 56-60

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Published

2024-12-31

How to Cite

[1]
Louise, D.M.-M. , David Mindja Eko, Astadjam Dairou and François Djomou 2024. Primary cervical neuroblastoma in children: clinical case and review of the literature. IPHO-Journal of Advance Research in Medical & Health Science. 2, 12 (Dec. 2024), 01–04. DOI:https://doi.org/10.5281/zenodo.14580572.